Cryolipolysis - a non-operative alternative to liposuction

For the cryolipolysis procedure

Cryolipolysis is a non-operative alternative to liposuction for the permanent removal of fat deposits through adipocyte apoptosis (fat cell killing). The process of apoptosis is natural for the body and is a programmed killing of fat cells caused by freezing and crystallization of 4 of the 5 fatty acids that make up the fat cell. Clinical studies have shown that cryolipolysis with the Cooltech Define freezes 90% of the adipose tissue that enters the applicator. The procedure is effective and safe. The guarantee for this is the device with which we, at Diyana Aesthetic House, work – Cooltech Define.

The device has a number of advantages over other devices operating on the principle of cryolipolysis. It has 9 applicators that are suitable for different parts of the body. The device has tips that allow you to treat hard-to-reach parts of the body, such as double chin, arms, knees, slings, even hard pants. The device has specially designed handles for hard pants. The device also has a large abdominal applicator. All this makes Cooltech Define a preferred machine among the leading aesthetic centers in Europe. The procedure with this device is extremely effective. It is clinically proven that after the first the result is up to 30% less fat in the treated area. The procedure is completely safe, as the machine works with specially designed and patented safety membranes. Their function is to protect the skin from frostbite and necrosis.

Cooltech Define also has 9 templates for correct determination of the size of the treated area and accurate diagnosis of the type of adipose tissue. This gives the therapist a great advantage and minimizes the risk of diagnostic error. The device is extremely cost-effective for any aesthetic center that wants to satisfy the need of its customers to shape their body.

Cooltech Define


To shape the silhouette

The cryolipolysis procedure is suitable for anyone with a normal physique and weight who needs to shape certain parts of their body. The procedure is not suitable for overweight people. It is not a means to lose weight, but to remove local fats and shape the body. The good effect of the procedure comes in combination with sports and healthy eating.

Safe procedure

The procedure is entirely safe. Its safety has been proven in clinical trials. Cooltech Define works with patented, specially designed protective membranes that protect the skin from excessive cold.

Efficient procedure

Cryolipolysis is a very efficient procedure. Correctly performed and diagnosed, it can reduce fatty tissue in the treated area by up to 30% after the first procedure. It also has an applicator for treating a double chin.

Get in shape!

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Frequently Asked Questions

Answers to the most common questions we get asked by our customers.

How does Cooltech Define technology work?

The Define cryoadipolysis system is used for treatment of localized fat deposits of varying skin fold thickness in people who are of normal weight or slightly overweight.

Define is a non-invasive treatment by which full body contouring can be achieved by applying controlled cooling of up to -11°C using the large applicators and up to -5°C with the small applicators.

The goal of this treatment is to gradually and permanently reduce the subcutaneous adipose tissue in the body by eliminating a large number of fat cells.

Is the procedure with Cooltech Define safe?


Due to their high content of fatty acids, fat cells are more susceptible to crystallization when subjected to low temperatures. However, the surrounding structures (fibrocytes, blood vessels, muscles, etc.) are more resistant to crystallization, so it is possible to induce apoptosis of localized fat cells while protecting the surrounding tissue.

Is the procedure right for me?

The system allows for the treatment of many different areas due to the different types of applicators offered by Define, which can be completely customized. Thanks to the various applicators, up to 4 areas can be treated in one session.

Колко сесии са необходими за оптимални резултати?

Понякога една сесия е достатъчна, за да имате задоволителен резултат. Разбира се, зависи от пациента и понякога са необходими повече процедури- до 4 на една и съща зона. Cooltech Define е единственият апарат в света за криолиполиза, който позволява да се третират до 4 зони в една сесия.

Potential side effects

During and immediately after the session:

  • Feeling of deep pulling or squeezing (frequent).
  • Severe itching or burning, tingling, pain or cramping (frequent).
  • Paresthesias, dysesthesias. Temporary skin sensitivity disorders (frequent).
  • Mild inflammation (frequent).
  • Allergic reaction to the compounds of the gel used in the membranes of the membranes themselves (very unusual).
  • Temporary localised pain (frequent).
  • Transient local erythema (frequent and reversible after a few hours).
  • Thermal injuries (very unusual).
  • Nausea, dizziness or vasovagal symptoms (very unusual).


After the session (from 24 hours onwards)

  • Temporary skin sensitivity disorders: numbness, compression and itching (frequent).
  • Temporary mild inflammation (frequent).
  • Hematomas (rare).
  • Temporary localised pain (frequent).
  • Local erythema or temporary whitening of the skin (rare).
  • Hyperplasia or swelling of the treated area (very unusual).
  • Unsatisfactory results (very unusual).
  • Nausea, dizziness or vasovagal syncope until normal body temperature stabilizes (very unusual).
  • Hyper or hypopigmentation, hardness, small nodules (very unusual).
  • Increase in pre-existing hernias in the treated area (very unusual).
  • In the submental region: disorders of the motor nerve in the perioral area (marginal mandibular and hypoglossal); dry mouth or decreased saliva production (extremely unusual).



  • Cryoglobulinemia or paroxysmal cold hemoglobinuria.
  • Periodontal disease (for treatment in the chin area.
  • Cold urticaria or Raynaud’s disease.
  • Impaired peripheral circulation.
  • Neuropathic diseases such as postherpetic neuralgia or diabetic neuropathy.
  • Skin sensitivity disorders.
  • Open or infected wounds in the treatment area.
  • Blood disorders or concomitant use of anticoagulants or antiaggregants.
  • Recent surgeries, scar tissue in or adjacent to the treatment area (treatment may be allowed only under physician’s supervision).
  • Hernia or history of hernia in or adjacent to the treatment area.
  • Active skin lesions, dermatitis, active psoriasis, open wounds, extremely sensitive or fragile skin in the treatment area.
  • History of local or recurrent skin infection. Acute infectious diseases.
  • Implanted devices such as pacemakers or defibrillators.
  • Hypoproteinemia.
  • Fever.
  • Chronic diseases with functional impairment (renal failure, heart failure, liver failure, etc.).
  • Infectious diseases with comorbidities (local or systemic).
  • Autoimmune diseases affecting the skin: SLE (systemic lupus erythematosus), scleroderma, Sjögren’s syndrome (dermatologic, rheumatologic).
  • Autoimmune peripheral neuropathies due to endocrine or metabolic disorders (diabetes), peripheral neuropathies of infectious or toxic origin.
  • Immunosuppression (HIV) and use of immunosuppressive drugs.
  • History of deep vein thrombosis in the treatment area, varicose veins, phlebitis, thrombophlebitis.
  • Active or recent malignancy (cancer) within the last 5 years, use of anticancer drugs.
  • Precancerous lesions / malignancies or suspected neoplasms in the treatment area.
  • History of fat tissue hyperplasia.
  • Long-term treatment with corticosteroids in the last 12 months.

After the treatment

The following should be avoided:

  • Prolonged exposure to sun or other heat sources such as saunas, hot springs or steam baths for a period of 7 days after the treatment.
  • Physical activities that may cause injury or in another way affect the treatment area.
  • Long travels (during the first 72 hours) increase fluid retention and may lead to increased discomfort.
  • Tight or uncomfortable clothing as some swelling is to be expected.


Adhere to the following:

  • If the treatment was performed on an area not covered by clothes, use a sunscreen with a SPF of 50 or higher daily.
  • Perform daily self-massage in the treatment area for at least the first 7 days after the treatment.
  • The use of compression garments is optional. Compression garments can be used for a period of between 7 and 30 days, as appropriate.
  • If necessary, use the painkillers that you use regularly to relieve general pain (paracetamol or similar) if you experience a non-neuralgic type of pain.
  • If the pain persists or worsens, the patient should consult a physician.






Cooltech Define Pricies

1 procedure800 BGN
3 procedures1600 BGN
6 procedures3200 BGN

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